principal investigator


William S. Talbot, Ph.D.

Catherine R. Kennedy and Daniel L. Grossman Fellow in Human Biology


Will is interested in the development and function of the vertebrate nervous system.  Will was an undergraduate at the University of Florida, where he conducted under-

graduate research with Prof. Edward (Ward) Wakeland and received his B.S. with

High Honors in Microbiology. He completed his Ph.D. in Biochemistry in 1993 with

an NSF Predoctoral Fellowship at Stanford University. As a graduate student with

Prof. David Hogness at Stanford, Will investigated the genetic control of metamor-

phosis in Drosophila. As a Jane Coffin Childs postdoctoral fellow with Prof. Charles

Kimmel at the University of Oregon, Will studied genes that regulate early develop-

ment in the zebrafish. In Eugene, Will also worked with Prof. John Postlethwait to

develop genetic mapping resources for the zebrafish. Will become an Assistant

Professor at the Skirball Institute of the NYU School of Medicine in 1996. In 1999,

Will joined Stanford University, where he is now a Professor of Developmental

Biology and Senior Associate Dean for Graduate Education and Postdoctoral Affairs.


postdoctoral researchers


Ana Meireles Sousa, Ph.D.


Ana received a B.S. with honors in Biology from the University of Porto. As an

Erasmus student, Ana conducted her undergraduate research at the laboratory of

Dr. Stefan Nobel at Stockholm University, studying apoptosis in liver cancer models.

After working for a year as a research assistant with Dr. Paula Soares at IPATIMUP,

addressing the molecular identity of thyroid cancer, Ana joined the graduate

program in Biomedicine and Experimental Biology at the University of Coimbra.

Under this program she joined the laboratory of Professor Hiro Ohkura at Edinburgh

University. Her graduate work focused on the mechanisms and molecules regulating

microtubule cytoskeleton dynamics in developing fruit flies. Ana joined the Talbot lab

in September 2011 to study the mechanisms that localize specific mRNAs to

myelin in oligodendrocytes and the role of the motor protein Kif1b in this process.

She has also identified microglia mutants and discovered that the phosphate

exporter Xpr1b has a specific function in microglia and other tissue macrophages.



Daniel E. Lysko, Ph.D.


Dan received a B.S. in Biochemistry and Molecular Biology from Penn State University.

As a Schreyer Honors College scholar, Dan conducted his undergraduate research

in Dr. Graham Thomas’ lab, studying spectrin repeat function during development

using fruit flies.  In his graduate work he investigated the cytoskeletal regulation

underlying the guidance of migrating neurons in the developing mouse brain in

Dr. Jeff Golden’s lab at the University of Pennsylvania/Children’s Hospital of

Philadelphia.  Dan joined the Talbot Lab in March 2015 and is investigating the

signaling interactions that regulate glial cell development and myelination.



graduate students



Harwin Sidik


With a National Science Scholarship from A*STAR, Harwin received a B.S. with

honors in molecular biology from the University of Wisconsin, Madison. As an

undergraduate, Harwin worked at the laboratory of Dr. Jing Zhang where he studied

the role of oncogenic K-ras mutations in leukemia and myeloma. Harwin then spent

a year in Singapore in the laboratory of Dr. Sai-Kiang Lim, where he explored the

trans-differentiation potentials of human mesenchymal stem cells. In 2010, Harwin

joined the Talbot lab to study the genetic control of oligodendrocyte development

and myelination in the central nervous system of zebrafish. In Fall 2015, Harwin will

be leaving (sunny) California, where he sometimes complains of “bitterly cold winter

days”, to return to (even sunnier) Singapore to do his postdoctoral research.



Kimberle Shen


Kimberle was an undergraduate at the University of Cambridge and graduated with

first class honors in Zoology in 2010. As an undergraduate, she spent a summer in

Prof. Constance Cepko's lab studying the translational regulation of rhodopsin in

mouse eye development. Kimberle then spent a year in Dr. Bruno Reversade's lab

at the Institute of Medical Biology in Singapore studying the genetics of monozygotic

twinning. With support from a National Science Scholarship from A*STAR, Kimberle

joined the Department of Developmental Biology at Stanford as graduate student

in September 2011. Kimberle is investigating the function of two genes with essential

functions in myelination and microglia.



lab manager



Tuky K. Reyes


Tuky was an undergraduate at the University of California, San Diego where she

conducted research with Dr. Martin Yanofsky studying fruit dehiscence in Arabidopsis

thaliana. She was recognized as an undergraduate research scholar for her efforts

in helping to identify the genes involved in seed dispersal. Tuky received a B.S. in

Biochemistry and Cell Biology. In 2002, she joined the Talbot Lab as a research

assistant, and has since provided technical support on a variety of projects. She

currently manages and maintains the zebrafish facility and provides zebrafish

husbandry training to all lab personnel.



talbot lab.  stanford school of medicine.  copyright © 2015.  all rights reserved.