people.
William S. Talbot, Ph.D.
Catherine R. Kennedy and Daniel L. Grossman Fellow in Human Biology
Will is interested in the development and function of the vertebrate nervous system. Will was an undergraduate at the University of Florida, where he conducted under-
graduate research with Prof. Edward (Ward) Wakeland and received his B.S. with
High Honors in Microbiology. He completed his Ph.D. in Biochemistry in 1993 with
an NSF Predoctoral Fellowship at Stanford University. As a graduate student with
Prof. David Hogness at Stanford, Will investigated the genetic control of metamor-
phosis in Drosophila. As a Jane Coffin Childs postdoctoral fellow with Prof. Charles
Kimmel at the University of Oregon, Will studied genes that regulate early develop-
ment in the zebrafish. In Eugene, Will also worked with Prof. John Postlethwait to
develop genetic mapping resources for the zebrafish. Will become an Assistant
Professor at the Skirball Institute of the NYU School of Medicine in 1996. In 1999,
Will joined Stanford University, where he is now a Professor of Developmental
Biology and Senior Associate Dean for Graduate Education and Postdoctoral Affairs.
postdoctoral researchers
Ana Meireles Sousa, Ph.D.
Ana received a B.S. with honors in Biology from the University of Porto. As an
Erasmus student, Ana conducted her undergraduate research at the laboratory of
Dr. Stefan Nobel at Stockholm University, studying apoptosis in liver cancer models.
After working for a year as a research assistant with Dr. Paula Soares at IPATIMUP,
addressing the molecular identity of thyroid cancer, Ana joined the graduate
program in Biomedicine and Experimental Biology at the University of Coimbra.
Under this program she joined the laboratory of Professor Hiro Ohkura at Edinburgh
University. Her graduate work focused on the mechanisms and molecules regulating
microtubule cytoskeleton dynamics in developing fruit flies. Ana joined the Talbot lab
in September 2011 to study the mechanisms that localize specific mRNAs to
myelin in oligodendrocytes and the role of the motor protein Kif1b in this process.
She has also identified microglia mutants and discovered that the phosphate
exporter Xpr1b has a specific function in microglia and other tissue macrophages.
Daniel E. Lysko, Ph.D.
Dan received a B.S. in Biochemistry and Molecular Biology from Penn State University.
As a Schreyer Honors College scholar, Dan conducted his undergraduate research
in Dr. Graham Thomas’ lab, studying spectrin repeat function during development
using fruit flies. In his graduate work he investigated the cytoskeletal regulation
underlying the guidance of migrating neurons in the developing mouse brain in
Dr. Jeff Golden’s lab at the University of Pennsylvania/Children’s Hospital of
Philadelphia. Dan joined the Talbot Lab in March 2015 and is investigating the
signaling interactions that regulate glial cell development and myelination.
graduate students
Harwin Sidik
With a National Science Scholarship from A*STAR, Harwin received a B.S. with
honors in molecular biology from the University of Wisconsin, Madison. As an
undergraduate, Harwin worked at the laboratory of Dr. Jing Zhang where he studied
the role of oncogenic K-ras mutations in leukemia and myeloma. Harwin then spent
a year in Singapore in the laboratory of Dr. Sai-Kiang Lim, where he explored the
trans-differentiation potentials of human mesenchymal stem cells. In 2010, Harwin
joined the Talbot lab to study the genetic control of oligodendrocyte development
and myelination in the central nervous system of zebrafish. In Fall 2015, Harwin will
be leaving (sunny) California, where he sometimes complains of “bitterly cold winter
days”, to return to (even sunnier) Singapore to do his postdoctoral research.
Kimberle Shen
Kimberle was an undergraduate at the University of Cambridge and graduated with
first class honors in Zoology in 2010. As an undergraduate, she spent a summer in
Prof. Constance Cepko's lab studying the translational regulation of rhodopsin in
mouse eye development. Kimberle then spent a year in Dr. Bruno Reversade's lab
at the Institute of Medical Biology in Singapore studying the genetics of monozygotic
twinning. With support from a National Science Scholarship from A*STAR, Kimberle
joined the Department of Developmental Biology at Stanford as graduate student
in September 2011. Kimberle is investigating the function of two genes with essential
functions in myelination and microglia.
lab manager
Tuky K. Reyes
Tuky was an undergraduate at the University of California, San Diego where she
conducted research with Dr. Martin Yanofsky studying fruit dehiscence in Arabidopsis
thaliana. She was recognized as an undergraduate research scholar for her efforts
in helping to identify the genes involved in seed dispersal. Tuky received a B.S. in
Biochemistry and Cell Biology. In 2002, she joined the Talbot Lab as a research
assistant, and has since provided technical support on a variety of projects. She
currently manages and maintains the zebrafish facility and provides zebrafish
husbandry training to all lab personnel.
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